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Hand hygiene01:23

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Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
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Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
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Chlorhexidine: An Elixir for Periodontics.

Arthiie Thangavelu1, Sahaya Stelin Kaspar2, Ramesh Periannan Kathirvelu3

  • 1Department of Periodontics, J. K. K. Nattraja Dental College, Komarapalyam, Tamil Nadu, India.

Journal of Pharmacy & Bioallied Sciences
|November 5, 2020
PubMed
Summary
This summary is machine-generated.

Chlorhexidine, a potent antibacterial agent, disrupts bacterial cell membranes, proving effective against a wide range of microbes. It is a gold standard in dentistry for preventing and treating periodontal disease.

Keywords:
Antisepticchemical plaque controlchlorhexidinemouthrinseperiodontal diseases

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Area of Science:

  • Microbiology
  • Pharmacology
  • Dentistry

Background:

  • Chlorhexidine is a cationic bisbiguanide with broad-spectrum antimicrobial properties.
  • It exhibits activity against gram-positive and gram-negative bacteria, yeasts, dermatophytes, and some viruses.
  • Widely recognized in dentistry, it is crucial for managing periodontal disease.

Purpose of the Study:

  • To provide a detailed review of chlorhexidine.
  • To elucidate its mechanism of action, indications, and various forms.
  • To summarize relevant research studies concerning chlorhexidine.

Main Methods:

  • Literature review of existing studies on chlorhexidine.
  • Analysis of scientific data on its antibacterial properties and clinical applications.
  • Compilation of information on its formulation and usage.

Main Results:

  • Chlorhexidine's antibacterial effect stems from disrupting bacterial cell membranes, increasing permeability, and causing cell lysis.
  • Demonstrated efficacy in treating and preventing periodontal disease.
  • Established as the gold standard in various dental applications.

Conclusions:

  • Chlorhexidine is a highly effective antimicrobial agent with a well-defined mechanism of action.
  • Its role in dentistry, particularly for periodontal health, is significant.
  • Further research and understanding of its applications continue to be important.