Feasibility of identifying reflection artifacts in photoacoustic imaging using two-wavelength excitation

One of the remaining challenges of bringing photoacoustic imaging to clinics is the occurrence of reflection artifacts. Previously, we proposed a method using multi-wavelength excitation to identify and remove the RAs. However, this method requires at least 3 wavelengths. Here we improve the method further by reducing the required number of wavelengths to 2. We experimentally demonstrate this new method and compare it with the previous one. Results show that this new method holds great feasibility for identifying reflection artifacts in addition to preserving all advantages of the previous method.