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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-Associated Urogenital Disease: A Current Update
Guangdi Chu1, Wei Jiao1, Fei Xie1
1Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Abstract:
Severe Acute Respiratory Syndrome Coronavirus 2, which is quickly spreading around the world and causes coronavirus disease 2019, may attack the urogenital system. We thought that a summary of the current literature about urogenital disease associated with the virus would be useful for physicians treating patients with coronavirus disease 2019. PubMed was comprehensively screened for studies published from 2019 to 2020. Studies of coronavirus disease 2019 patients with kidney disease, reproductive system diseases, or urological cancer were included. Through reviewing current literature, we summarized that acute kidney injury is a risk factor for patients with coronavirus disease 2019 and is related to their survival. A diagnosis of chronic kidney disease increases the risk of infection. The therapy for kidney transplant patients should be cautious and implemented on a case-by-case basis. When the public health burden is too heavy to bear, a rational selection of treatment for patients with urological cancer is vital. The male reproductive system is at high risk of being attacked by the virus, which may cause damage to reproductive function, and the long-term effects require further study. So, the complications associated with the urogenital system should not be ignored during the course of infection treatment and more robust evidence of long-term effects on the urogenital system will be proposed as more studies are published.
Insights
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) can impact the urogenital system. Physicians should monitor kidney function, reproductive health, and urological conditions in patients with coronavirus disease 2019 (COVID-19).
Area of Science:
- Urology
- Nephrology
- Infectious Diseases
Background:
- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a global pandemic causing coronavirus disease 2019 (COVID-19).
- Emerging evidence suggests SARS-CoV-2 may affect the urogenital system.
- Understanding these effects is crucial for managing COVID-19 patients.
Purpose of the Study:
- To summarize current literature on urogenital diseases associated with SARS-CoV-2.
- To provide guidance for physicians treating COVID-19 patients with urogenital complications.
Main Methods:
- Comprehensive literature search of PubMed from 2019 to 2020.
- Inclusion of studies on COVID-19 patients with kidney disease, reproductive system diseases, or urological cancer.
Main Results:
- Acute kidney injury is a risk factor and impacts survival in COVID-19 patients.
- Chronic kidney disease diagnosis increases infection risk; kidney transplant patient management requires caution.
- The male reproductive system is vulnerable to SARS-CoV-2, potentially affecting function; long-term effects need further investigation.
- Urological cancer treatment selection is vital during public health crises.
Conclusions:
- Urogenital system complications should be considered in COVID-19 management.
- Further research is needed to establish the long-term effects of SARS-CoV-2 on the urogenital system.
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