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Related Experiment Video

Updated: Dec 2, 2025

Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods

Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods

Published on: June 6, 2025

PubChem in 2021: new data content and improved web interfaces.

Sunghwan Kim¹, Jie Chen¹, Tiejun Cheng¹

¹National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, 20894, USA.

Nucleic Acids Research

|November 5, 2020

Summary

This summary is machine-generated.

PubChem, a chemical information resource, has been significantly enhanced with new data sources, updated interfaces, and new services like Pathway pages. A special collection for COVID-19 research was also created.

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Area of Science:

Biochemistry
Chemistry
Bioinformatics

Background:

PubChem is a widely used chemical information resource with millions of monthly users.
Recent years have seen significant development and expansion of PubChem's capabilities.

Purpose of the Study:

To detail the substantial improvements and new features implemented in PubChem over the past two years.
To highlight the expansion of data sources, user interface updates, and new service offerings.

Main Methods:

Integration of data from over 100 new sources, including chemical-literature, property, and patent data.
Updates to PubChem's homepage and record pages, including a data model change.
Introduction of new services such as the Periodic Table, Element pages, Pathway pages, and Knowledge panels.

Main Results:

Expanded chemical and biological data through new data sources.
Improved user experience with faster information retrieval via updated interfaces.
Enhanced programmatic access and new functionalities for users.
Established a dedicated COVID-19 data collection for SARS-CoV-2 research.

Conclusions:

PubChem has undergone significant enhancements, improving data accessibility and user experience.
The expanded resources and new features strengthen PubChem's role as a vital chemical information hub.
The creation of a COVID-19 specific collection demonstrates PubChem's responsiveness to global health crises.