Related Experiment Video
Updated: Dec 2, 2025

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
Published on: February 28, 2025
Opioid Use and Misuse in Pregnancy
1Department of Anesthesiology, Emory University Hospital Midtown, 550 Peachtree Street Northeast, Atlanta, GA 30308, USA.
Opioid use disorder in pregnant women is rising, leading to serious complications for both mother and baby. Educating patients and tailoring pain management are key to addressing this public health crisis.
Area of Science:
- Obstetrics and Gynecology
- Addiction Medicine
- Public Health
Background:
- The incidence of opioid use disorder (OUD) among pregnant individuals has dramatically increased over the last two decades.
- This rise mirrors the trend observed in the general population, highlighting a significant public health concern.
Purpose of the Study:
- To review the complications associated with opioid use during pregnancy.
- To explore potential strategies for mitigating the impact of OUD on maternal and infant health outcomes.
Main Methods:
- This review synthesizes existing literature on OUD in pregnancy.
- It examines the spectrum of adverse outcomes and discusses current and proposed management approaches.
Main Results:
- Pregnancies complicated by opioid use exhibit substantially elevated rates of neonatal opioid withdrawal syndrome (NOWS), intrauterine growth restriction, neural tube defects, and stillbirth.
- Maternal risks include increased mortality, heightened postpartum pain, and prolonged hospitalizations.
Conclusions:
- Effective patient education regarding the risks and benefits of multimodal analgesia is crucial.
- Empowering shared decision-making and individualizing pain management strategies are essential to combat the opioid epidemic in pregnant populations.
Related Concept Videos
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Opioid Analgesics: Morphine and Other Natural Cogeners
Analgesia and Pain Management
Prescription, Nonprescription and Orphan Drugs
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Opioid Receptors: Overview
Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...

