Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cement disease.

L C Jones, D S Hungerford

    Clinical Orthopaedics and Related Research
    |December 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Cement disease, a pathologic condition around loosened cemented prostheses, exists and can lead to joint failure. While effective for some, methyl methacrylate cement poses long-term challenges for active patients, necessitating alternative solutions.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Augmented Reality From the Benchtop to the Practice of Joint Arthroplasty: Is It Feasible?

    The Journal of arthroplasty·2022
    Same author

    An evidence-based guide to the treatment of osteonecrosis of the femoral head.

    The bone & joint journal·2017
    Same author

    The photoelectric measurement of fluorescence spectra.

    Journal of the Optical Society of America·2010
    Same author

    A STUDY OF THE NUCLEOSIDE TRI- AND DIPHOSPHATE ACTIVITIES OF RAT LIVER MICROSOMES.

    The Journal of cell biology·2009
    Same author

    Of mice and men, periodic limb movements and iron: how the human genome informs the mouse genome.

    Genes, brain, and behavior·2008
    Same author

    Identification of marker genes including RUNX3 (AML2) that discriminate between different myeloproliferative neoplasms and normal individuals.

    Leukemia·2008
    Same journal

    Impact Microindentation Evaluates Bone Strength, Bone Quality, and Fracture Susceptibility Across Skeletal Sites: A Cadaver Study.

    Clinical orthopaedics and related research·2026
    Same journal

    What Is the Effect of Robot Reduction in Displaced Pelvic Fractures? A Multicenter Randomized Clinical Trial.

    Clinical orthopaedics and related research·2026
    Same journal

    CORR Insights®: Acute or Delayed TKA for Tibial Plateau Fracture? An Observational Study From the Swedish Arthroplasty Register.

    Clinical orthopaedics and related research·2026
    Same journal

    Reply to the Letter to the Editor: Guest Editorial: Recalling a Recall.

    Clinical orthopaedics and related research·2026
    Same journal

    Radial Head Fractures Cluster in the Anterolateral and Anteromedial Quadrants and Do Not Correlate With Coronoid Fracture Types.

    Clinical orthopaedics and related research·2026
    Same journal

    Reduced Cerebellar Activation With Eyes Closed Is Associated With Delayed Peroneal Reaction Time in Patients With Chronic Ankle Instability.

    Clinical orthopaedics and related research·2026
    See all related articles

    Area of Science:

    • Orthopedic Surgery
    • Biomaterials Science
    • Pathology

    Background:

    • Loosened cemented prostheses create an abnormal bony environment.
    • This condition, termed 'cement disease,' can progress to joint failure, pain, and functional inhibition.
    • The biomaterial properties of the cement itself contribute to this pathologic state.

    Purpose of the Study:

    • To determine if "cement disease" is a valid pathologic entity.
    • To discuss the role of methyl methacrylate cement in joint prosthesis loosening.
    • To explore the limitations of cement fixation and the need for alternatives.

    Main Methods:

    • Review of existing literature on cemented joint prostheses.
    • Analysis of the pathophysiology of cement loosening.

    Related Experiment Videos

  • Evaluation of the properties of methyl methacrylate cement.

    • Main Results:

    • "Cement disease" is confirmed as a distinct pathologic condition.
    • Methyl methacrylate cement has limitations for young, active, or overweight patients.
    • Current improvements in technique and cement handling can reduce loosening incidence.

    Conclusions:

    • Eliminating "cement disease" requires eliminating cement in certain patient populations.
    • Alternatives such as novel grouting materials or cementless prostheses (press-fit or biologic ingrowth) are needed.
    • Cement remains suitable for elderly, less active patients with shorter life expectancies.