A recurrent lung abscess caused by delayed diagnosis of unique co-infection with Abiotrophia defectiva

Ilaria Onorati1, Patrice Guiraudet1, Typhaine Billard-Pomares2

  • 1Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Avicenne, Chirurgie Thoracique et Vasculaire, Université Paris 13, Sorbonne Paris Nord, Paris, France.

Insights

A rare lung abscess co-infection involving Prevotella baroniae and nutritionally variant streptococci (NVS) led to treatment failure. Early detection of NVS is crucial for effective management of pulmonary abscesses.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Pulmonology

Background:

  • Lung abscesses are serious infections requiring prompt diagnosis and treatment.
  • Prevotella baroniae is a known pathogen, but co-infections, especially with nutritionally variant streptococci (NVS), are less understood in pulmonary contexts.

Observation:

  • A 48-year-old patient presented with a lung abscess.
  • The abscess was caused by a co-infection of Prevotella baroniae and Abiotrophia defective, a type of NVS.
  • Diagnosis of the NVS co-infection was delayed.

Findings:

  • The co-infection with NVS contributed to multiple medical treatment failures.
  • Surgical intervention became necessary due to the complexity of the infection.
  • Abiotrophia defective (NVS) is challenging to detect in pulmonary abscesses.

Implications:

  • This case underscores the importance of considering and systematically testing for NVS co-infections in lung abscesses.
  • Failure to identify NVS may lead to prolonged illness and treatment resistance.
  • Awareness of NVS in pulmonary infections can improve patient outcomes and guide therapeutic strategies.

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