Epilepsy-Definition, Classification, Pathophysiology, and Epidemiology.

Jessica Falco-Walter1

  • 1Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Palo Alto, California.

Seminars in Neurology
|November 6, 2020
PubMed
Summary

Accurate definitions and classifications for seizures and epilepsy are crucial for proper diagnosis, treatment, and research. This article clarifies contemporary understanding of these neurological conditions.

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Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
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Seizures: Classification01:13

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Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
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