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Bowman Layer Transplantation-A Review
Jack S Parker1,2, Philip W Dockery3, Gerrit R J Melles2,4,5
1Parker Cornea, Birmingham, AL.
Asia-Pacific Journal of Ophthalmology (Philadelphia, Pa.)
|November 6, 2020
Summary
Bowman layer (BL) transplantation is a versatile treatment for corneal conditions like scarring and keratoconus. Its unique properties offer a minimally immune-reactive option for improving corneal health and shape.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Tissue Engineering
Background:
- Bowman layer (BL) transplantation is utilized for diverse corneal pathologies.
- Indications include postrefractive surgery haze, herpetic scarring, and keratoconus.
Purpose of the Study:
- To review the historical context of BL transplantation.
- To discuss recent advancements and future directions in BL transplantation procedures.
Main Methods:
- Review of existing literature on BL transplantation.
- Analysis of the properties and clinical applications of BL grafts.
Main Results:
- BL transplantation demonstrates versatility due to its robust, thin, and acellular nature.
- Transplanted BL effectively inhibits stromal scarring and flattens ectatic corneas.
- The procedure carries a minimal risk of immune rejection.
Conclusions:
- BL transplantation is a valuable and adaptable surgical technique.
- Its unique biological properties contribute to successful outcomes across various corneal diseases.
- Future developments are anticipated to further refine and expand its applications.

