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Towards real-time free-hand biopsy navigation.

Clément Beitone1, Gaëlle Fiard1,2, Jocelyne Troccaz1

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This study introduces a faster, more accurate 2D/3D ultrasound registration method for navigated prostate biopsies. The improved technique enhances cancer detection by providing continuous, real-time tracking of biopsy trajectories.

Keywords:
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Area of Science:

  • Medical Imaging
  • Surgical Navigation
  • Prostate Cancer Diagnostics

Background:

  • Transrectal ultrasound (TRUS) guided prostate biopsy is crucial for cancer detection.
  • Current 2D ultrasound imaging limits visibility of cancerous tissue and anatomical context.
  • Navigated prostate biopsy requires precise localization of the biopsy trajectory.

Purpose of the Study:

  • To present a rigid 2D/3D ultrasound (US) registration method for navigated prostate biopsy.
  • To enable continuous localization of the biopsy trajectory during the procedure.
  • To improve accuracy and processing time compared to previous methods.

Main Methods:

  • An organ-based approach for real-time rigid registration without external probe localization devices.
  • Combines image similarity and geometric proximity of detected features.
  • Utilizes a multi-level approach with a rejection rate for improved accuracy and speed.

Main Results:

  • The current method is 12–17% more accurate and 20–60 times faster than its previous version.
  • Dynamic registration experiments show successful continuous tracking of biopsy location at 5–15 Hz.
  • Evaluations performed on a large dataset under routine clinical conditions.

Conclusions:

  • On-the-fly 2D/3DUS registration is efficient for biopsy trajectories.
  • This method facilitates advancements in prostate navigation.
  • The technique is suitable for clinical transfer and improved prostate cancer detection.