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Published on: February 26, 2018
Chest imaging in paediatric pulmonary TB
Tanyia Pillay1, Savvas Andronikou2, Heather J Zar3
1Department of Paediatrics & Child Health, and SA-MRC unit on Child and Adolescent Health, University of Cape Town, South Africa; Department of Radiology, Chris Hani Baragwanath Academic Hospital, South Africa.
Insights
Diagnosing childhood tuberculosis (TB) is difficult due to non-specific symptoms. This review explores advanced imaging techniques like CT and MRI for better pulmonary TB diagnosis and complication assessment in children.
Area of Science:
- Pediatric Infectious Diseases
- Radiology
- Medical Imaging
Background:
- Tuberculosis (TB) is a leading infectious cause of death globally.
- Diagnosing pulmonary TB in children presents challenges due to vague symptoms, specimen collection difficulties, and low bacterial counts.
- Plain radiograph findings for pediatric pulmonary TB are often non-specific, complicating diagnosis.
Purpose of the Study:
- To review the benefits and characteristics of cross-sectional imaging modalities.
- To evaluate the utility of ultrasound, CT, and MRI in diagnosing pediatric pulmonary TB.
- To assess the role of these imaging techniques in identifying TB complications in children.
Main Methods:
- Review of current literature on cross-sectional imaging for pediatric pulmonary TB.
- Analysis of imaging features of pulmonary TB on ultrasound, CT, and MRI.
- Evaluation of diagnostic accuracy and complication detection capabilities.
Main Results:
- Cross-sectional imaging offers advantages over plain radiographs in diagnosing pediatric pulmonary TB.
- CT and MRI provide detailed anatomical information, aiding in the identification of TB and its complications.
- Ultrasound can be a useful adjunct, particularly for pleural effusions and superficial lymphadenopathy.
Conclusions:
- Advanced cross-sectional imaging techniques like CT and MRI are valuable tools for diagnosing pulmonary TB in children.
- These modalities improve the detection of TB complications and aid in treatment monitoring.
- Integrating advanced imaging can overcome the limitations of conventional radiography in pediatric TB diagnosis.
Abstract:
Tuberculosis (TB) remains a significant cause of death from an infectious disease worldwide. The diagnosis of pulmonary TB in children is often challenging as children present with non-specific clinical symptoms, have difficulties providing specimens and have a low bacillary load. Radiological imaging supports a clinical diagnosis of pulmonary TB in children, can assess response to treatment and evaluate complications of TB. However, radiological signs on plain radiographs are often non-specific and inter-observer variability in the interpretation contribute to the difficulties in radiological interpretation and diagnosis. The goal of this review is to discuss the advantages and features of cross-sectional imaging such as ultrasound, Computed tomography (CT) and Magnetic resonance imaging (MRI) in diagnosing pulmonary TB (PTB) and its complications in children.
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