Related Experiment Video
Updated: Dec 1, 2025

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness
Published on: March 18, 2022
Quantitative Assessment of the Mandibular Condyle in Patients With Rheumatoid Arthritis Using Diffusion-Weighted
Naohisa Hirahara1, Takashi Kaneda2, Hirotaka Muraoka1
1Assistant Professor, Department of Radiology, Nihon University School of Dentistry at Matsudo, Chiba, Japan.
Purpose:
The purpose of this study was to quantitatively assess the mandibular condyle in patients with rheumatoid arthritis (RA) using the apparent diffusion coefficient (ADC) on diffusion-weighted imaging (DWI).
Patients And Methods:
Thirty-one patients with RA and temporomandibular joint (TMJ) pain who underwent magnetic resonance imaging (MRI) examination of the TMJs at our hospital between August 2006 and March 2020 were included in this study. Twenty-one patients with normal TMJs who underwent MRI examination at our hospital between August 2006 and March 2020 were included as controls. The MRI findings were compared between the 2 groups.
Results:
The mean ADC values of the mandibular condyle in patients with RA were 1.20 ± 0.17 × 10-3 mm2/second. The mean ADC values of the mandibular condyle in patients with RA were significantly greater than the controls (P < .01). Receiver operating characteristic curve analysis revealed a cutoff of 0.89 for the ADC values of the mandibular condyle in patients with RA. The receiver operating characteristic curve analysis revealed areas under the curve for maximum ADC values of 0.98.
Conclusions:
Our study found that the ADC on DWI could be used for the quantitative assessment of the mandibular condyle in patients with RA, which indicated that the ADC on DWI could be useful for predicting RA.

