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Published on: February 23, 2014
[Rare infections of the lungs not endemic in Germany]
Frieder Pfäfflin1, Miriam Songa Stegemann1
1Medizinische Klinik mit Schwerpunkt Infektiologie und Pneumologie, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Deutschland.
Abstract:
This article describes viral, bacterial, fungal and parasitic infections, which are not endemic and little known in Germany. Avian influenza, Middle East respiratory syndrome (MERS) and the plague can all lead to severe pulmonary complications with a high mortality. In addition, there is a risk of nosocomial spread and therefore patients must always be isolated. Melioidosis, blastomycosis, paracoccidioidomycosis, and histoplasmosis are primarily often misclassified as community-acquired pneumonia due to typical causative organisms. A detailed anamnesis focussing on exposure in endemic areas is key to the diagnosis. Paragonimiasis is often manifested a few weeks after consumption of raw seafood and pronounced eosinophilia is typical. Relevant aspects of the epidemiology, clinical course, treatment and, if applicable, prevention are presented as cases of these diseases can occur at any time in Germany.
Insights
This article details rare, non-endemic infections like avian influenza, MERS, and plague, emphasizing their pulmonary risks and isolation needs. It also covers misdiagnosed fungal and parasitic diseases, highlighting travel history for accurate diagnosis.
Area of Science:
- Infectious Diseases
- Tropical Medicine
- Public Health
Context:
- Focuses on infections not typically endemic to Germany, posing diagnostic challenges.
- Highlights the risk of severe pulmonary complications and nosocomial spread.
- Emphasizes the importance of travel history and exposure in endemic areas for diagnosis.
Purpose:
- To describe the epidemiology, clinical presentation, and management of rare, non-endemic infections.
- To raise awareness among healthcare professionals about these diseases.
- To provide guidance on diagnosis and prevention strategies.
Summary:
- Discusses viral (Avian Influenza, MERS), bacterial (Plague, Melioidosis), fungal (Blastomycosis, Paracoccidioidomycosis, Histoplasmosis), and parasitic (Paragonimiasis) infections.
- Details potential severe pulmonary complications, high mortality rates, and the necessity of patient isolation.
- Explains common misclassifications, particularly with fungal infections mimicking community-acquired pneumonia, and the diagnostic value of anamnesis and eosinophilia.
Impact:
- Aims to improve the recognition and timely diagnosis of these uncommon but serious infections in Germany.
- Contributes to better patient management and potentially reduces mortality and morbidity.
- Enhances preparedness for the occurrence of imported infectious diseases.
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