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The Potential of Synthetic Biology for Trichoderma reesei
Roland Martzy1, Astrid R Mach-Aigner2
1Christian Doppler Laboratory for Optimized Expression of Carbohydrate-Active Enzymes, Institute of Chemical, Environmental and Bioscience Engineering, TU Wien, Vienna, Austria.
Abstract:
Within the last 20 years, ground-breaking progress has been made in the field of synthetic biology, enabling the construction of novel pathways up to entire synthetic genomes in both prokaryotic and eukaryotic organisms. These innovations are primarily adapted for biotechnological applications, where filamentous fungi such as Trichoderma reesei are widely used to produce various enzymes of industrial interest. In the following chapter, we provide a broad overview on the current progress involving this particular organism, covering studies on synthetic promoters and transcription factors as well as synthetic expression platforms. Furthermore, this chapters aims to be a short introduction to the present book since many methods mentioned here are described in detail in the subsequent chapters.
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