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Related Concept Videos

Phases of Wound Repair01:28

Phases of Wound Repair

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Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
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Updated: Dec 1, 2025

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
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Wound Phototherapy.

Laura L Bolton1

  • 1Adjunct Associate Professor, Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ.

Wounds : a Compendium of Clinical Research and Practice
|November 9, 2020
PubMed
Summary
This summary is machine-generated.

Low-level light therapy (LLLT) shows promise for wound healing, with systematic reviews clarifying its effects on dermatologic conditions and diabetic foot ulcers. Further research is needed to optimize LLLT parameters for diverse wound types.

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Area of Science:

  • Dermatology and Wound Healing
  • Photomedicine
  • Biotechnology

Background:

  • Low-level light therapy (LLLT) utilizes lasers or LEDs for therapeutic effects.
  • LLLT is approved in the US for various dermatologic conditions and pain management.
  • Global use of LLLT spans several years for diverse medical applications.

Purpose of the Study:

  • To systematically review the efficacy of light-emitting diodes (LEDs) on dermatologic conditions and wounds.
  • To evaluate the effects of LLLT on diabetic foot ulcers (DFUs).
  • To provide clarity on LLLT's role in wound management.

Main Methods:

  • Systematic review of existing literature on LED therapy for skin conditions.
  • Systematic review focusing on LLLT for diabetic foot ulcers.
  • Analysis of studies evaluating different wavelengths and parameters of LLLT.

Main Results:

  • LLLT demonstrates potential benefits for specific dermatologic conditions and wound healing.
  • Evidence suggests LLLT may be effective in managing diabetic foot ulcers.
  • Variability in LLLT parameters (wavelength, dose) contributes to diverse outcomes.

Conclusions:

  • LLLT, particularly using LEDs, offers a viable therapeutic option for wound management.
  • Further high-quality randomized clinical trials are necessary to establish optimal LLLT protocols.
  • LLLT warrants consideration for its role in treating chronic and acute wounds, including DFUs.