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Mimics of vasculitis.

Ernest Maningding1, Tanaz A Kermani1

  • 1Division of Rheumatology, University of California, Los Angeles, Los Angeles, CA, USA.

Rheumatology (Oxford, England)
|November 9, 2020
PubMed
Summary
This summary is machine-generated.

Prompt vasculitis diagnosis requires recognizing mimics. A vessel size-based approach helps differentiate vasculitis from mimics like infections, genetic disorders, and other conditions, preventing harmful misdiagnoses.

Keywords:
aneurysmcalciphylaxischolesterol emboliendocarditismimicsthrombosisvasculitisvasculopathy

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Area of Science:

  • Rheumatology
  • Neurology
  • Vascular Medicine

Background:

  • Prompt diagnosis of vasculitis is crucial for effective treatment.
  • Recognizing conditions that mimic vasculitis is equally important to avoid misdiagnosis and inappropriate therapy.
  • Vasculitis mimics can present with diverse clinical manifestations affecting various organ systems.

Purpose of the Study:

  • To highlight the importance of identifying vasculitis mimics.
  • To outline a systematic approach for differentiating vasculitis from its mimics based on vessel size.
  • To discuss common mimics and their characteristics.

Main Methods:

  • Review of literature on vasculitis and its mimics.
  • Categorization of mimics based on affected vessel size (large, medium, small).
  • Discussion of clinical features and diagnostic considerations for each mimic.

Main Results:

  • Infections, genetic disorders, vasculopathies, cholesterol emboli, thrombotic conditions, calciphylaxis, and reversible cerebral vasoconstriction syndrome are key mimics.
  • A vessel size-based approach is useful for evaluating suspected vasculitis.
  • Mimics can affect cutaneous, renal, and central nervous system (CNS) manifestations.

Conclusions:

  • Accurate differentiation of vasculitis from its mimics is essential to prevent adverse outcomes.
  • A systematic approach considering vessel size aids in distinguishing vasculitis from mimics.
  • Clinical vigilance for mimics is imperative in suspected vasculitis cases.