Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Reye syndrome].

E Gladtke1, U Schauseil-Zipf

  • 1Universitäts-Kinderklinik Köln.

Monatsschrift Kinderheilkunde : Organ Der Deutschen Gesellschaft Fur Kinderheilkunde
|October 1, 1987
PubMed
Summary
This summary is machine-generated.

Reye's syndrome is a rare but serious condition often preceded by viral infections. This study details its incidence in Western Germany, noting potential links to medications like aspirin and paracetamol.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[The use and benefit of the 'children with special health care needs screener' in the paediatric school entrance examinations 2004/2005 in Cologne].

Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))·2014
Same author

Analysis of cancellous bone turnover by multiple slice analysis at distal radius: a study using peripheral quantitative computed tomography.

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry·2002
Same author

Analysis of the musculoskeletal system in children and adolescents receiving anticonvulsant monotherapy with valproic acid or carbamazepine.

Pediatrics·2001
Same author

[Fluoride prophylaxis].

Deutsche medizinische Wochenschrift (1946)·1993
Same author

[Pregnancy outcome with intensified insulin therapy in manifest diabetes].

Geburtshilfe und Frauenheilkunde·1990
Same author

Severe intra-uterine growth retardation: obstetrical management and follow up studies in children born between 1970 and 1985.

European journal of obstetrics, gynecology, and reproductive biology·1989

Area of Science:

  • Pediatric Neurology
  • Toxicology
  • Epidemiology

Context:

  • Reye's syndrome presents with diverse clinical, laboratory, and histopathological features.
  • Etiology remains debated, though viral infections (Influenza B, A, varicella) are common preceding factors.
  • Genetic predisposition and exogenic factors (aflatoxins, certain medications) are implicated.

Purpose:

  • To present the clinical course, laboratory findings, and histopathological features of Reye's syndrome.
  • To investigate the incidence and characteristics of Reye's syndrome in Western Germany between 1983-1985.
  • To explore potential etiological and pathogenetic aspects, including environmental and pharmaceutical factors.

Summary:

  • A 1983-1985 inquiry involving 99 major pediatric hospitals in Western Germany reported 15 cases of Reye's syndrome.

Related Experiment Videos

  • The incidence was estimated at 0.04-0.05 per 100,000 children under 18, with an average of 5 cases annually.
  • Eight fatalities were recorded; three patients had received acetylsalicylic acid and two paracetamol prior to symptom onset.

    • Impact:

    • Highlights geographical variations in Reye's syndrome incidence, with higher rates in the US and UK compared to other European countries.
    • Provides crucial epidemiological data on Reye's syndrome in Western Germany during a specific period.
    • Underscores the importance of considering viral triggers and potential medication associations, such as acetylsalicylic acid and paracetamol, in Reye's syndrome cases.