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Updated: Dec 1, 2025

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Published on: May 10, 2024
Closed Incision Negative Pressure Therapy: Indications and Adherence to Protocol
Sina Foroutanjazi1,2, Michael Jonczyk1, Lilian Chen1
1Department of Surgery, Tufts Medical Center, USA.
Closed incision negative pressure therapy (CINPT) is increasingly used for wound management. Key patient indicators for CINPT include a BMI over 30, smoking, and diabetes mellitus, suggesting appropriate clinical application.
Area of Science:
- Surgical innovation
- Wound healing research
- Clinical practice guidelines
Background:
- Wound management complications increase morbidity, mortality, and healthcare costs.
- Closed incision negative pressure therapy (CINPT) offers a potential improvement over traditional methods.
- Current Food and Drug Administration (FDA) indications for CINPT are broad, raising questions about patient selection.
Purpose of the Study:
- To identify common clinical indications for CINPT.
- To establish a consensus on appropriate candidates for CINPT.
- To determine if patient demographics influence CINPT decision-making.
Main Methods:
- A comprehensive literature review of 57 articles was performed.
- The American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database was utilized.
- Data from over 11,000 patients receiving CINPT were analyzed.
Main Results:
- Obesity (BMI >30), smoking, and diabetes mellitus were consistently identified as primary indications for CINPT.
- Obesity was noted in 47.1% (NSQIP) and 39.6% (literature) of patients.
- Diabetes mellitus was present in 22.7% (NSQIP) and 47.9% (literature) of patients.
Conclusions:
- High BMI, smoking, and diabetes mellitus are the most frequent indications for CINPT.
- These findings aid in identifying patients most likely to benefit from CINPT.
- The study supports adherence to literature-based practice guidelines for CINPT in wound management.
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