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Updated: Dec 1, 2025

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Isolation, Culture, and Characterization of Prostate Cancer-Associated Fibroblasts
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Immune cell profiling in Gleason 9 prostate cancer patients treated with brachytherapy versus external beam
H Wang1, L C Mendez2, G Morton3
1Department of Medical Biophysics, University of Toronto, Canada; Sunnybrook Research Institute, Toronto, Canada.
Abstract:
This exploratory study evaluates immunological changes in high-risk Gleason 9 prostate cancer patients treated with EBRT+BT compared to EBRT alone. Notably, BT demonstrates the potential to elicit a T cell response which may support further investigation using circulating immune cells as predictive and prognostic biomarkers for radiotherapy response.

