COVID-KOP: integrating emerging COVID-19 data with the ROBOKOP database
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Published on: February 11, 2022
Daniel Korn1, Tesia Bobrowski2, Michael Li1
1Department of Computer Science, University of North Carolina at Chapel Hill, USA.
Summary:
In response to the COVID-19 pandemic, we established COVID-KOP, a new knowledgebase integrating the existing Reasoning Over Biomedical Objects linked in Knowledge Oriented Pathways (ROBOKOP) biomedical knowledge graph with information from recent biomedical literature on COVID-19 annotated in the CORD-19 collection. COVID-KOP can be used effectively to generate new hypotheses concerning repurposing of known drugs and clinical drug candidates against COVID-19 by establishing respective confirmatory pathways of drug action.
Availability And Implementation:
COVID-KOP is freely accessible at https://covidkop.renci.org/. For code and instructions for the original ROBOKOP, see: https://github.com/NCATS-Gamma/robokop.
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