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Physicians' knowledge regarding epinephrine underuse in anaphylaxis.

Joaquin A Pimentel-Hayashi1, Elsy M Navarrete-Rodriguez1, Oscar I Moreno-Laflor1

  • 1Department of Allergy and Immunology, WAO Center of Excellence, Hospital Infantil de México Federico Gomez, Mexico City, Mexico.

Asia Pacific Allergy
|November 12, 2020
PubMed
Summary
This summary is machine-generated.

Physician knowledge gaps regarding anaphylaxis diagnosis and treatment contribute to epinephrine underuse. Improving education on recognizing anaphylaxis and correct epinephrine administration is crucial for better patient outcomes.

Keywords:
AnaphylaxisAttitudesEpinephrineKnowledgeSurveys and questionnaires

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Area of Science:

  • Allergy and Immunology
  • Emergency Medicine
  • Clinical Practice

Background:

  • Anaphylaxis is a severe, life-threatening hypersensitivity reaction.
  • Underuse of epinephrine in anaphylaxis patients is linked to adverse outcomes.
  • Epinephrine use in anaphylaxis cases may be as low as 8%.

Purpose of the Study:

  • To determine the proportion of physicians aware that epinephrine is the primary treatment for anaphylaxis.
  • To identify knowledge deficits in anaphylaxis diagnosis and management contributing to epinephrine underuse.

Main Methods:

  • An online survey with a 10-item questionnaire was administered to physicians in Mexico City.
  • Statistical analysis included measures of central tendency and the chi-square test.
  • The survey assessed knowledge of anaphylaxis diagnosis, treatment, and epinephrine administration.

Main Results:

  • Only 2.6% of physicians answered all 10 anaphylaxis knowledge questions correctly.
  • While 72.4% identified epinephrine as first-line treatment, only 49.5% would administer it intramuscularly.
  • Significant gaps were observed in recognizing anaphylaxis without cutaneous symptoms, contraindications, correct dosing, and epinephrine autoinjector prescription.

Conclusions:

  • Physician knowledge gaps in anaphylaxis recognition and management persist.
  • Low rates of correct diagnosis, appropriate epinephrine use, and prescription of autoinjectors contribute to epinephrine underuse.
  • Targeted educational interventions are needed to improve anaphylaxis care and reduce epinephrine underuse in clinical practice.