Imaging biomarkers in upper gastrointestinal cancers
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Updated: Nov 30, 2025

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
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Michela Gabelloni1, Lorenzo Faggioni1, Emanuele Neri1
1Department of Translational Research, Diagnostic and Interventional Radiology, University of Pisa, Pisa, Italy.
Abstract:
In parallel with the increasingly widespread availability of high performance imaging platforms and recent progresses in pathobiological characterisation and treatment of gastrointestinal malignancies, imaging biomarkers have become a major research topic due to their potential to provide additional quantitative information to conventional imaging modalities that can improve accuracy at staging and follow-up, predict outcome, and guide treatment planning in an individualised manner. The aim of this review is to briefly examine the status of current knowledge about imaging biomarkers in the field of upper gastrointestinal cancers, highlighting their potential applications and future perspectives in patient management from diagnosis onwards.
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