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A Retrospective Analysis of the Trends in Acute Appendicitis During the COVID-19 Pandemic
Paige Finkelstein1, Omar Picado2, Kiranmayi Muddasani1
1Department of Surgery, Mount Sinai Medical Center, Miami Beach, Florida, USA.
Insights
During COVID-19 quarantine, patients with appendicitis had a higher perforation rate. This led to longer hospital stays and more complications, indicating negative health impacts from public health orders.
Area of Science:
- Surgery
- Public Health
- Infectious Diseases
Background:
- COVID-19 pandemic led to public health mandates like "safer at home" orders.
- These restrictions deterred patients from seeking hospital care, potentially affecting outcomes for acute conditions.
- The impact of these restrictions on appendicitis outcomes was previously unexamined.
Purpose of the Study:
- To determine if there was an increased rate of perforated appendicitis during COVID-19 quarantine.
- To analyze procedural interventions, length of stay, and complication rates for appendicitis during this period.
Main Methods:
- Retrospective analysis comparing March-May 2020 (quarantine) with March-May 2019.
- Data collected from a single healthcare system including a regional referral center and three ERs.
- Included patients presenting with acute appendicitis; perforation determined radiographically or intraoperatively.
Main Results:
- 48 appendicitis cases during quarantine vs. 59 the prior year; perforated cases rose from 10 to 16 (17% to 33%).
- Perforated appendicitis patients had longer symptom duration, higher white blood cell counts, and longer operative times.
- Perforated cases were associated with increased length of stay and complication rates.
Conclusions:
- A significant increase in perforated appendicitis rates was observed during the COVID-19 quarantine period.
- Delayed presentation due to public health orders negatively impacted appendicitis outcomes.
- Perforated appendicitis during quarantine resulted in longer hospital stays, increased operative times, and higher complication rates.
Abstract:
The corona virus disease of 2019 (COVID-19) imposed new public health constraints that deterred people from coming to the hospital. The outcome of patients who developed appendicitis during mandated COVID-19 quarantine has yet to be examined. The main objective was to establish whether there was an increased rate of perforated appendicitis seen during COVID-19 quarantine. Secondary objectives included observing the type of procedure performed, length of stay, and associated complications. This retrospective analysis was designed to look at the rates of appendicitis and perforated appendicitis observed during mandatory "safer at home order" from March to May 2020. The same time period a year earlier was used for comparative analysis. The study utilized data gathered from a single health care system, which consisted of a large regional referral center with three emergency rooms (ERs). Patients were included in the study if they presented to any ER in our health care system with a chief complaint of acute appendicitis. Perforated appendicitis was determined either radiographically or intraoperatively. Interventions included surgery, percutaneous drainage, or medical management. There were 107 patients who were included. During quarantine, a total of 48 patients presented with acute appendicitis, with 16 perforations, compared with the previous year where 59 patients presented with acute appendicitis, with 10 perforations (33% versus 17% P = .04). Most patients underwent laparoscopic appendectomy (91%, n = 98), six patients (6%) were managed with intravenous antibiotics and 3 patients (3%) with percutaneous drainage. Patients who perforated had a longer duration of symptoms (2 versus 1, P = .03), white blood cell count (13,190 versus 15,960 cells/mm3, P = .09), and longer operative time (72 versus 89 minutes, P = .01). Patients who perforated had an increased length of stay and rate of complication. There was an overall increased rate of perforated appendicitis seen during quarantine compared with the previous year. Patients with perforated appendicitis had an increased length of stay, longer operative time, and increased rate of complications. Thus, although people were staying home due to public health safety orders, it negatively impacted those who developed appendicitis who may have presented to the hospital otherwise sooner.
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