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Updated: Nov 30, 2025

Author Spotlight: Development and Characterization of Eco-Friendly Lignin-Based Microparticles for Enhanced Delivery of Bioflavonoids
Published on: March 1, 2024
Towards Green Nanoscience: From extraction to nanoformulation.
Amaia Huguet-Casquero1, Eusebio Gainza2, Jose Luis Pedraz3
1NanoBioCel Group, Laboratory of Pharmaceutics, University of the Basque Country (UPV/EHU), School of Pharmacy, Paseo de la Universidad 7, Vitoria- Gasteiz 01006, Spain; Biosasun S.A, Iturralde 10, Etxabarri-Ibiña, Zigoitia 01006, Spain.
Green Nanoscience offers sustainable methods for organic nanoparticle production, addressing safety concerns in biomedicine. This review explores eco-friendly routes for designing safe and effective nanoformulations.
Area of Science:
- Biotechnology and Nanomedicine
- Green Chemistry and Sustainable Engineering
Background:
- Nanotechnology has transformed various sectors, including medicine, but faces scrutiny due to safety risks and side effects.
- Green Nanoscience/Nanotechnology offers a solution by promoting sustainable processes to mitigate nanotoxicity.
- The application of green principles to organic nanoparticle development, widely used in biomedicine, is still in its early stages.
Purpose of the Study:
- To review and discuss potential green routes for the design and elaboration of organic nanoparticles.
- To highlight the importance of implementing specific green principles for organic nanoparticle formulation.
- To provide a comprehensive overview of eco-friendly strategies within Green Nanoscience for organic nanoparticles.
Main Methods:
- Literature review focusing on sustainable processes in nanoparticle lifecycle.
- Analysis of green extraction methods for nanomaterials and active compounds.
- Exploration of eco-friendly nanoformulation techniques for organic nanoparticles.
Main Results:
- While green approaches are established for inorganic nanoparticles, organic nanoparticle synthesis requires dedicated green strategies.
- Sustainable processes can be applied across the entire lifecycle of nanoformulation, from material sourcing to final product.
- Various green routes exist for the extraction and formulation of organic nanoparticles.
Conclusions:
- There is a critical need to advance Green Nanoscience for organic nanoparticles due to their prevalence in biomedicine.
- Implementing green principles in organic nanoparticle design is essential for ensuring safety and sustainability.
- This review outlines key strategies for the eco-friendly elaboration of organic nanoparticles, paving the way for safer biotechnological applications.

