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Doppler Optical Coherence Tomography of Retinal Circulation
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Optical Coherence Tomography Angiography in Uveitic Glaucoma - A Pilot Study.
C Lommatzsch1, P Bauermann1, B Heimes-Bussmann1
1Department of Ophthalmology, St. Franziskus Hospital, Muenster, Germany.
Ocular Immunology and Inflammation
|November 13, 2020
Summary
Optical coherence tomography angiography (OCTA) reveals reduced vessel density (VD) in uveitic eyes with glaucoma. OCTA effectively detects these vascular changes in the optic nerve and macula.
Area of Science:
- Ophthalmology
- Medical Imaging
Background:
- Uveitic glaucoma (UG) presents unique challenges in vascular assessment.
- Optical coherence tomography angiography (OCTA) offers high-resolution imaging of ocular vasculature.
Purpose of the Study:
- To compare vessel density (VD) using OCTA in eyes with uveitic glaucoma (UG) versus uveitic eyes without glaucoma (UV), primary open-angle glaucoma (POAG), and healthy eyes (HY).
Main Methods:
- VD measurements were performed using OCTA across radial peripapillary capillaries, superficial (SL) and deep vascular plexuses (DL), and the choroid.
- Comparative analysis was conducted among UG, UV, POAG, and HY groups.
Main Results:
- Significantly lower VD was observed in papillary areas of the UG group compared to healthy eyes (HY).
- The superficial vascular plexus (SL) showed significantly reduced whole VD in the UG group compared to HY.
- Choroidal VD was significantly lower in the UG group than in the UV group in specific quadrants.
Conclusions:
- OCTA is a valuable tool for identifying differences in vessel density within the papillary and macular regions of eyes with uveitic glaucoma.
- These findings highlight potential vascular compromise in UG that can be detected non-invasively.
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