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Cerebral Venous Sinus Thrombosis in the COVID-19 Pandemic

Chaitanya B Medicherla1, Rachel A Pauley, Adam de Havenon

  • 1Department of Neurology (CM, RAP, SY, KI, JT), New York University Langone Medical Center, New York, New York; and Department of Neurology (AdH), University of Utah School of Medicine, Salt Lake City, Utah.

Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society
|November 13, 2020
PubMed

Insights

Coronavirus Disease 2019 (COVID-19) is linked to an increased risk of cerebral venous sinus thrombosis (CVST), a rare but serious clotting condition. This review details CVST

Area of Science:

  • Neurology
  • Ophthalmology
  • Infectious Diseases

Background:

  • Emerging evidence suggests a link between Coronavirus Disease 2019 (COVID-19) and an increased incidence of thromboembolic events.
  • Cerebral venous sinus thrombosis (CVST) has been identified as a significant neuro-ophthalmologic complication associated with COVID-19.

Purpose of the Study:

  • To provide a comprehensive overview of cerebral venous sinus thrombosis (CVST) in the context of COVID-19.
  • To discuss the epidemiology, clinical presentation, diagnostic approaches, pathophysiology, and management strategies for CVST related to COVID-19.

Main Methods:

  • Systematic review of the existing scientific literature.
  • Analysis of reported cases and studies concerning CVST and COVID-19.

Main Results:

  • Cerebral venous sinus thrombosis (CVST) is an infrequent thromboembolic condition with diverse clinical manifestations and etiological factors.
  • Neurological sequelae of CVST can be severe, potentially leading to profound visual impairment and mortality.
  • The COVID-19 pandemic appears to significantly influence the risk and presentation of CVST.

Conclusions:

  • Increased vigilance regarding the presentation, pathogenesis, and management of CVST is warranted due to its association with COVID-19.
  • Understanding the interplay between COVID-19 and CVST is crucial for effective patient care and outcomes.
Abstract

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