Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

282
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
282

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Follicular Mucinosis Associated with Adult T-Cell Leukemia-Lymphoma.

The American Journal of dermatopathology·2026
Same author

Stealth Pigmented Squamous Cell Carcinoma in Situ: An Undescribed Variant With Deceptive Clinical and Histological Features.

The American Journal of dermatopathology·2026
Same author

New-onset erythrodermic psoriasis associated with antiepileptic drug use.

Dermatology online journal·2026
Same author

TRBC1 Immunohistochemistry Utilization in Formalin-fixed Paraffin-embedded Tissue as an Adjunct to T-cell Clonality Testing in the Assessment of Cutaneous Lymphoproliferative Disorders.

The American journal of surgical pathology·2026
Same author

Photodistributed exfoliative dermatitis associated with semaglutide: Expanding the spectrum of glucagon-like peptide-1 receptor agonist-associated cutaneous reactions.

JAAD case reports·2026
Same author

Expression and prognostic value of cyclase-associated proteins in cutaneous melanoma.

Melanoma research·2026

Related Experiment Video

Updated: Nov 30, 2025

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs
11:36

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

Published on: April 21, 2012

22.4K

Cutaneous leishmaniasis successfully treated with miltefosine.

Cynthia X Chan1, Brian J Simmons2, John E Call2

  • 1Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.

Cutis
|November 13, 2020
PubMed
Summary

Two cases of New World cutaneous leishmaniasis were treated successfully with oral miltefosine. Prompt diagnosis and treatment are crucial for preventing severe outcomes of this neglected tropical disease.

More Related Videos

In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice
06:57

In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice

Published on: February 20, 2020

8.5K
A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line
12:22

A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line

Published on: December 30, 2012

22.7K

Related Experiment Videos

Last Updated: Nov 30, 2025

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs
11:36

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

Published on: April 21, 2012

22.4K
In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice
06:57

In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice

Published on: February 20, 2020

8.5K
A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line
12:22

A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line

Published on: December 30, 2012

22.7K

Area of Science:

  • Tropical medicine
  • Infectious diseases
  • Dermatology

Background:

  • Leishmaniasis is a neglected tropical disease with increasing global prevalence.
  • Globalization contributes to the rising incidence of leishmaniasis in non-endemic regions like the United States.

Observation:

  • Two adult cases of New World cutaneous leishmaniasis (Leishmania Viannia) were diagnosed in New England.
  • Both patients had recently traveled to Central America and reported underutilizing sand fly bite prevention measures.

Findings:

  • Successful treatment was achieved using oral miltefosine, which was well-tolerated by both patients.
  • Miltefosine demonstrates efficacy, tolerability, and ease of administration, supporting its consideration as a first-line agent.

Implications:

  • Early diagnosis and treatment are vital to reduce morbidity and mortality, especially for species with mucocutaneous spread potential.
  • Collaborative efforts between medical specialties and public health organizations like the CDC are essential for effective leishmaniasis management.
  • Vector avoidance remains the primary preventive strategy against leishmaniasis transmission.