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Isolation of Viral Replication Compartment-enriched Sub-nuclear Fractions from Adenovirus-infected Normal Human Cells
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Adenoviral E1A Exploits Flexibility and Disorder to Target Cellular Proteins

Maria Grazia Murrali1, Isabella C Felli1, Roberta Pierattelli1

  • 1Department of Chemistry "Ugo Schiff" and Magnetic Resonance Center (CERM), University of Florence, Via Luigi Sacconi 6, 50019 Sesto Fiorentino (Florence), Italy.

Biomolecules
|November 14, 2020
PubMed
Summary

This study characterizes the dynamic interaction between Adenovirus E1A protein and a flexible region of human CREB-binding protein (CBP-ID4). Nuclear magnetic resonance reveals new insights into fuzzy complex formation in viral oncogenesis.

Keywords:
CBPE1AIDPNMRfuzzy complex

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