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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
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Retrospective Observational Study on Riboflavin Prophylaxis in Child and Adolescent Migraine.
1Pediatric Headache Program, Department of Neurology, The University of Texas at Austin Dell Medical School, Austin, Texas.
Pediatric Neurology
|November 14, 2020
Summary
Riboflavin significantly reduced headache frequency, intensity, and duration in pediatric migraineurs. This safe and inexpensive nutraceutical is recommended for migraine prevention in children.
Area of Science:
- Neurology
- Pediatrics
- Nutraceuticals
Background:
- Migraine is a common neurological disorder in children.
- Effective and safe treatment options for pediatric migraine are needed.
Purpose of the Study:
- To evaluate the efficacy of riboflavin in preventing migraine in pediatric patients.
- To assess the impact of riboflavin on headache frequency, intensity, and duration.
Main Methods:
- Retrospective observational study of 42 pediatric migraineurs (aged 6-18).
- Weight-based dosing of riboflavin was recommended for migraine prevention.
- Nonparametric tests were used to analyze changes in headache parameters.
Main Results:
- Significant reduction in monthly headache days (21.90 to 11.07 days, P < 0.001).
- Marked decrease in headache intensity (8.85 to 2.30, P < 0.001) and duration (18.23 to 10.18 hours, P = 0.001).
- Positive correlation between riboflavin efficacy and reduced acute medication use (r=0.304, P=0.05).
Conclusions:
- Riboflavin effectively reduces headache frequency, intensity, and duration in pediatric migraine.
- Riboflavin is a safe, inexpensive, and effective nutraceutical for pediatric migraine treatment.
- Recommended for reducing missed school days and acute medication use.
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