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Game-based movement facilitates acute priming effect in stroke.

Hyosok Lim1,2, Pooja C Iyer1,2, Cristian Luciano3

  • 1Brain Plasticity Laboratory, Department of Physical Therapy, University of Illinois at Chicago, Chicago, IL, USA.

Somatosensory & Motor Research
|November 16, 2020
PubMed
Summary
This summary is machine-generated.

Game-based ankle movement priming significantly enhanced corticomotor excitability in stroke survivors. This approach shows promise for improving motor function and recovery after stroke.

Keywords:
Transcranial magnetic stimulationanklecortical priminggaitgamificationstroke

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Area of Science:

  • Neuroscience
  • Rehabilitation Medicine
  • Motor Control

Background:

  • Cortical priming is a developing strategy for enhancing motor recovery post-stroke.
  • Limited research exists on lower limb movement-based priming's neuromodulatory effects on corticomotor excitability in stroke survivors.

Purpose of the Study:

  • To investigate the feasibility and effectiveness of game-based ankle movement priming on corticomotor excitability and motor performance.
  • To assess the impact of DIG-I-PRIME™ on chronic stroke survivors.

Main Methods:

  • Nineteen chronic stroke survivors underwent a 20-minute game-based priming session.
  • Transcranial magnetic stimulation (TMS) measured corticomotor excitability of the tibialis anterior (TA) muscle.
  • Motor performance was evaluated by tracking a sinusoidal target wave.

Main Results:

  • Game-based priming significantly increased ipsilesional corticomotor excitability by 25% (p=0.02).
  • No significant changes in corticomotor excitability were observed during the control (rest) condition.
  • No significant changes in motor performance were detected.

Conclusions:

  • Game-based ankle movement priming demonstrated a significant acute priming effect on the ipsilesional primary motor cortex (M1).
  • These findings offer preliminary evidence for the potential of game-based priming in promoting functional recovery after stroke.