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Native wild plants in Karachi, Pakistan: Rich source of antioxidant raw material
Mehreen Lateef1, Sadia Farheen1, Beena Naqvi2
1Pharmaceutical Research Center, Pakistan Council of Scientific and Industrial Research, Karachi, Pakistan.
Abstract:
Extracts of nine plants were studied for DPPH radical scavenging and reducing abilities. Pentatropis spiralis, Calotropis procera, Helitropium curassavicum, Withania somnifera and Chenopodium album showed reducing power ranging from 34% to 146%. Suaeda fruticosa, Trianthema portulacastrum, Pluchea lanceolata and Rumex dentatus has excellent antioxidant potential proved by their DPPH scavenging and reducing power. 1000µg/10µl chloroform extract of S. fruticosa gave 92% scavenging with IC50 value less than 0.7µg/10µl while its hexane extract possessed 80% reducing activity at 100µg/10µl concentration. DPPH free radical scavenging by methanolic extract of Trianthema portulacastrum was 60% and 76% at 1000 and 100µg/10µl respectively with IC50 value of 0.03µg/10µl while the reducing activity of 124% at 100µg/10µl. Methanolic extract of P. lanceolata showed 91% and 70% scavenging activity at 1000 and 100µg/10µl with IC50 value of 0.7µg/ 10µl. Reducing power is comparable with the reference BHA standard that is 98% at 100µg/10µl concentration. Rumex dentatus' extracts are excellent DPPH scavengers and hydrogen donators produced 156% reduction. Chloroform extract was inefficient antioxidant. These results make these plants a candidate for future research for treating ailments due to imbalance in free radicals.
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