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Human Cognitive Ability Is Modulated by Aromatase Availability in the Brain in a Sex-Specific Manner

Nelly Alia-Klein1, Rebecca N Preston-Campbell2, Sung Won Kim3

  • 1Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

Frontiers in Neuroscience
|November 16, 2020
PubMed
Summary

Brain aromatase availability impacts cognitive performance differently in men and women. Higher amygdala aromatase is linked to lower cognition in men, but not women, suggesting sex-specific effects.

Keywords:
PET[11C]vorozoleamygdalaaromatasecognitionestrogenhuman braintestosterone

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