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Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
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COVID-19 in China: From epidemiology to treatment (Review)

Hongtao Chen1,2, Shipin Wu1, Xiaoyong Zhang3

  • 1Department of Infectious Diseases, The Second Clinical Medical College, Shenzhen People's Hospital, Jinan University, Shenzhen, Guangdong 518020, P.R. China.

Experimental and Therapeutic Medicine
|November 16, 2020
PubMed

Insights

This review covers Coronavirus disease 2019 (COVID-19), a novel infectious disease caused by SARS-CoV-2. It details the prevalence, etiology, pathology, clinical signs, diagnosis, and treatment of COVID-19 in China.

Area of Science:

  • Infectious Diseases
  • Public Health
  • Virology

Background:

  • Coronavirus disease 2019 (COVID-19) emerged in Wuhan, China, in December 2019.
  • Caused by the novel SARS-CoV-2, it rapidly spread globally.
  • Initial symptoms included pneumonia, fever, cough, and fatigue.

Purpose of the Study:

  • To review the prevalence of COVID-19 in China.
  • To outline the etiology, pathology, and clinical presentation of the disease.
  • To discuss diagnostic methods and treatment strategies for COVID-19.

Main Methods:

  • Literature review of COVID-19 cases and research.
  • Analysis of epidemiological data from China.
  • Synthesis of information on clinical characteristics and diagnostic findings.

Main Results:

  • As of March 9, 2020, China reported 80,924 confirmed cases and 3,140 deaths.
  • The review details the infectious nature and rapid transmission of SARS-CoV-2.
  • Key clinical features, laboratory findings, and imaging results are presented.

Conclusions:

  • COVID-19 represents a significant global health challenge.
  • Understanding the disease's characteristics is crucial for effective management.
  • This review provides a comprehensive overview of early findings on COVID-19 in China.

Keywords:
COVID-19coronavirusepidemiologypathologytreatment

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