Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Color Vision01:24

Color Vision

1.1K
Color perception begins in the retina, the light-sensitive layer at the back of the eye. Two main theories explain how colors are seen: the trichromatic theory and the opponent-process theory. The trichromatic theory, proposed by Thomas Young in 1802 and extended by Hermann von Helmholtz in 1852, suggests that color vision is based on three types of cone receptors in the retina. These cones are sensitive to different but overlapping ranges of wavelengths corresponding to red, blue, and green.
1.1K
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

8.1K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
8.1K
Anatomy of the Eyeball01:20

Anatomy of the Eyeball

8.9K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
8.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Brexpiprazole for anxiety symptoms in people living with schizophrenia: a plain language summary.

Expert review of clinical pharmacology·2026
Same author

Evaluating the Risk of <i>Clostridioides difficile</i> Infection After Rifaximin Treatment for Small Intestinal Bacterial Overgrowth.

Journal of clinical medicine·2026
Same author

The importance of patient life engagement as a treatment goal in adults living with schizophrenia: a plain language summary.

Current medical research and opinion·2026
Same author

Easy and versatile preparation of <sup>68</sup>Ga- and Al<sup>18</sup>F-labelled arylphosphonium salts from a common precursor: stability and preliminary in vivo PET/CT evaluation.

EJNMMI radiopharmacy and chemistry·2026
Same author

Safety of Live Attenuated MMR, Varicella, and Yellow Fever Vaccination in Patients with Inflammatory Bowel Disease Receiving Biologic and Targeted Synthetic Therapy: A Propensity-Score-Matched Analysis.

Vaccines·2026
Same author

Amoxicillin Direct Oral Challenge in Hospitalized Patients With High-Risk Allergic Reactions, in a Pharmacist-Directed Program.

Open forum infectious diseases·2026
Same journal

The Role of Nrf2 in SIRT1-Mediated RGC Neuroprotection in Traumatic Optic Neuropathy.

Translational vision science & technology·2026
Same journal

Explicit Inclusion of Diabetes Mellitus Without Retinopathy Within Diabetic Retinopathy Prediction.

Translational vision science & technology·2026
Same journal

Preclinical Safety and Feasibility Study of Line-Field Confocal Optical Coherence Tomography for Ophthalmology Applications.

Translational vision science & technology·2026
Same journal

Pathogenicity Analysis of Two Novel CRB1 Mutations in Three Chinese Inherited Retinal Dystrophy Families and a Literature Review.

Translational vision science & technology·2026
Same journal

Gas-Lesion Contact and Postural Compliance After Vitrectomy With Tamponade: A Continuous Monitoring and 3D Quantitative Analysis.

Translational vision science & technology·2026
Same journal

Automated Deep Learning Quantification of Avascular Area and Intravitreal Neovascularization in Retinal Flatmounts of Rodent Oxygen-Induced Retinopathy Models.

Translational vision science & technology·2026
See all related articles

Related Experiment Video

Updated: Nov 30, 2025

Visualizing Visual Adaptation
04:43

Visualizing Visual Adaptation

Published on: April 24, 2017

9.4K

Quantifying Color Vision Changes Associated With Cataracts Using Cone Contrast Thresholds.

Urmi Mehta1,2, Anna Diep3, Kevin Nguyen4

  • 1Gavin Herbert Eye Institute, Department of Ophthalmology, University of California, Irvine, Irvine, California, USA.

Translational Vision Science & Technology
|November 17, 2020
PubMed
Summary
This summary is machine-generated.

The high-definition cone contrast test (CCT) reliably measures age-related and cataract-induced color vision decline. Cataract surgery significantly improves color vision across all cone types, aiding patient care.

Keywords:
age-related decline in color visioncolor vision changes associated with agingcolor vision changes before and after cataract surgerycone contrast testcone contrast threshold

More Related Videos

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
07:12

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Published on: April 11, 2025

722
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.6K

Related Experiment Videos

Last Updated: Nov 30, 2025

Visualizing Visual Adaptation
04:43

Visualizing Visual Adaptation

Published on: April 24, 2017

9.4K
Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
07:12

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Published on: April 11, 2025

722
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.6K

Area of Science:

  • Ophthalmology
  • Vision Science
  • Gerontology

Background:

  • Age and cataracts significantly impact color vision.
  • Quantifying these changes is crucial for understanding visual decline and treatment efficacy.

Purpose of the Study:

  • To evaluate the effects of aging and cataractous changes on color vision using the high-definition cone contrast test (CCT).
  • To assess the reliability of CCT under various testing conditions.

Main Methods:

  • Healthy volunteers and patients with cataracts underwent CCT.
  • Data analyzed included age, lens status, and CCT scores before and after cataract surgery.
  • Linear regression modeled age-related changes in cone sensitivity.

Main Results:

  • CCT scores were most reliable without mydriasis or pinhole correction.
  • Aging led to a decline in S-cone, M-cone, and L-cone sensitivity, with S-cones declining fastest.
  • Pseudophakic subjects showed improved S-cone sensitivity compared to phakic individuals.
  • Cataract surgery significantly improved CCT scores for all cone types.

Conclusions:

  • CCT provides a clinically practical method for quantifying color vision improvements post-cataract surgery.
  • CCT can assess age-related vision decline and cataract severity, guiding surgical decisions for optimal patient outcomes.