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Otosclerosis in an Urban Population
Jonathan S Choi1, Alex D Sweeney1, Ibrahim Alava2
1Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine.
Summary
Otosclerosis is most prevalent in Hispanic individuals, particularly those born abroad, suggesting environmental factors, not ethnicity, influence its occurrence. This may be linked to differing measles vaccination rates historically.
Area of Science:
- Otolaryngology
- Epidemiology
- Public Health
Background:
- Otosclerosis is a bone disease affecting the middle ear, leading to hearing loss.
- Its prevalence and risk factors in diverse urban populations require ongoing investigation.
Purpose of the Study:
- To determine the prevalence of otosclerosis within a large, urban public health system.
- To analyze demographic and geographic factors associated with otosclerosis diagnosis.
Main Methods:
- Retrospective review of 672,839 patients from January 2010 to August 2019.
- Analysis of diagnostic data (audiometry, CT scans) and patient demographics (sex, age, ethnicity, country of birth).
Main Results:
- 134 otosclerosis cases identified, with an overall prevalence of 20 per 100,000.
- Hispanics showed the highest prevalence (43 per 100,000), especially foreign-born individuals (60 per 100,000).
- Foreign-born Hispanics had a 3.69 times higher odds of otosclerosis compared to US-born Hispanics.
Conclusions:
- Otosclerosis prevalence is significantly influenced by country of birth, particularly among Hispanic populations.
- Environmental factors, potentially related to historical measles immunization rates, are likely drivers rather than inherent ethnic susceptibility.
- Further research into environmental influences on otosclerosis is warranted.
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