Biopolymeric Delivery Systems for Cosmetic Applications Using Chlorella vulgaris Algae and Tea Tree Essential Oil

Area of Science:

• Biomaterials Science
• Cosmetic Science
• Sustainable Chemistry

Background:

• Consumer demand for premium, eco-friendly cosmetics drives innovation in biomolecule delivery systems.
• Biocompatible and biodegradable materials are essential for advanced dermic applications.
• Developing effective delivery systems for natural bioactives like microalgae and essential oils is crucial.

Purpose of the Study:

• To develop a cellulose-based 3D matrix for retaining and releasing bioactive compounds from microalgae (Chlorella vulgaris) and tea tree essential oil.
• To optimize the matrix's porosity and pore structure using computational tools for enhanced dermic delivery.
• To evaluate the controlled release capabilities of the developed delivery system.

Main Methods:

• Fabrication of a 3D matrix using microfibrillated cellulose, nanofibrillated cellulose, carboxymethylcellulose, and alginate.
• Optimization of matrix structure using 3D computational modeling.
• Characterization of biopolymer structures via SEM, EDX, FTIR-ATR, and DSC.
• Assessment of controlled release of tea tree essential oil and microalgae components.

Main Results:

• Successful incorporation of microalgae and tea tree essential oil into a stable 3D cellulose-based matrix.
• Demonstrated controlled release of essential oil biomolecules, preventing premature vaporization.
• Optimized matrix structure confirmed through advanced characterization techniques.
• Enhanced retention and release profile of therapeutic biomolecules compared to free compounds.

Conclusions:

• The developed cellulose-based delivery system is a promising platform for encapsulating and controlling the release of bioactive compounds for cosmetic and dermic applications.
• The system improves the stability and efficacy of natural ingredients by extending their therapeutic exposure time.
• This biodegradable and biocompatible matrix offers a competitive advantage for premium, sustainable skincare products.