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Related Concept Videos

Acute Coronary Syndrome III: Diagnostic Studies01:30

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Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
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Related Experiment Video

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Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
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Multicentric Atrial Strain COmparison between Two Different Modalities: MASCOT HIT Study.

Matteo Cameli1, Marcelo Haertel Miglioranza2, Julien Magne3,4

  • 1Department of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, Italy.

Diagnostics (Basel, Switzerland)
|November 18, 2020
PubMed
Summary
This summary is machine-generated.

The QRS-LASr method for left atrial strain measurement is slightly more feasible and faster than P-LASr. Both methods show similar reproducibility in echocardiography analysis.

Keywords:
left atrial strainmulti-centric studyreference pointspeckle tracking echocardiographystandardization

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Area of Science:

  • Cardiology
  • Echocardiography
  • Medical Imaging Analysis

Background:

  • Left atrial (LA) strain measurement using speckle tracking echocardiography is crucial for assessing cardiac function.
  • Two primary methods exist: QRS-triggered (QRS-LASr) and P wave-triggered (P-LASr), differing in their analysis reference timing.
  • The MASCOT HIT study aimed to compare the reproducibility, feasibility, and time efficiency of these two LA strain methods.

Purpose of the Study:

  • To determine which left atrial strain measurement method, QRS-LASr or P-LASr, offers superior reproducibility.
  • To evaluate and compare the feasibility of performing QRS-LASr versus P-LASr in diverse patient populations.
  • To assess and compare the time required for analysis using both QRS-LASr and P-LASr techniques.

Main Methods:

  • A multi-center study involving 26 expert echocardiography centers analyzed LA strain in 938 subjects.
  • Two echocardiographers (young and senior) performed blinded analyses using both QRS-LASr and P-LASr methods.
  • Included participants were healthy controls, patients with arterial hypertension/aortic stenosis (LA pressure overload), and mitral regurgitation/heart failure (LA volume-pressure overload).

Main Results:

  • Inter-correlation coefficients (ICC) were comparable between QRS-LASr (0.93) and P-LASr (0.90), indicating similar reproducibility.
  • Feasibility was slightly higher for QRS-LASr (90-95%) compared to P-LASr (85-88%) across echocardiographer experience levels.
  • Analysis time was marginally lower for QRS-LASr (median 110s) than P-LASr (median 120s) for both young and senior echocardiographers.

Conclusions:

  • Both QRS-LASr and P-LASr are feasible and reproducible methods for left atrial strain assessment in a broad patient spectrum.
  • The QRS-LASr method demonstrates a slight advantage in feasibility and a reduction in analysis time compared to P-LASr.
  • QRS-LASr is recommended as a potentially more efficient and practical approach for routine clinical application in LA strain analysis.