Applications of CMOS Devices for the Diagnosis and Control of Infectious Diseases

Area of Science:

• Biomedical Engineering
• Infectious Disease Diagnostics
• Sensor Technology

Background:

• Emerging infectious diseases (e.g., COVID-19, Ebola, SARS, MERS) pose significant global health threats.
• Accurate and timely diagnosis is critical for controlling infectious disease outbreaks.
• Traditional diagnostic methods can be slow and resource-intensive.

Purpose of the Study:

• To provide an overview of complementary metal-oxide-semiconductor (CMOS) based sensor devices for infectious disease diagnosis.
• To highlight the advantages of CMOS technology in developing advanced diagnostic tools.
• To explore the potential of CMOS sensors in point-of-care (PoC) and lab-on-chip (LoC) applications.

Main Methods:

• Review of various CMOS-based sensor technologies.
• Discussion of optical, electrochemical, magnetic, and mechanical sensor designs.
• Analysis of CMOS sensor performance characteristics (accuracy, throughput, speed).

Main Results:

• CMOS technology offers high accuracy, high throughput, and rapid measurements for disease diagnosis.
• Low cost, low power consumption, and scalability are key advantages of CMOS sensors.
• CMOS sensors facilitate the development of powerful diagnostic devices like PoC systems and LoC platforms.

Conclusions:

• CMOS-based sensors are a promising technology for accurate and timely diagnosis of infectious diseases.
• These sensors can significantly contribute to global health security by enabling rapid response to outbreaks.
• The versatility of CMOS technology supports the creation of innovative diagnostic solutions for diverse medical needs.