Related Experiment Video
Updated: Nov 30, 2025
Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
Published on: November 8, 2024
Cervical Spine Alignment in the Sagittal Axis: A Review of the Best Validated Measures in Clinical Practice
Michael L Martini1, Sean N Neifert1, Emily K Chapman1
1Department of Neurosurgery, 5925Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Study Design:
Review of the best-validated measures of cervical spine alignment in the sagittal axis.
Objective:
Describe the C2-C7 Cobb Angle, C2-C7 sagittal vertical axis, chin-brow to vertical angle, T1 slope minus C2-C7 lordosis, C2 slope, and different types of cervical kyphosis.
Methods:
Search PubMed for recent technical literature on radiograph-based measurements of the cervical spine.
Results:
Despite the continuing use of measures developed many years ago such as the C2-C7 Cobb angle, there are new radiographic parameters being published and utilized in recent years, including the C2 slope. Further research is needed to compare older and newer measures for cross-validation. Utilizing these measures to determine the degree of correction intraoperatively and postoperatively will enable surgeons to optimize patient-level outcomes.
Conclusion:
Cervical spinal deformity can be a debilitating condition characterized by cervical spinal misalignment that affects the elderly more commonly than young populations. Many of these validated measures of cervical spinal alignment are useful in clinical settings due to their ease of implementation and correlations with various postoperative and health-related quality of life outcomes.
Related Concept Videos
01:16Vertebral Column: Regions and Curvature
Regions of the Vertebral Column
In an adult, the spine is subdivided into five regions: the cervical, the thoracic, the lumbar, the sacral, and the coccygeal region. The spine initially develops as a series of 33 vertebrae; after 20 years of age, the nine bones in the sacral region, five sacral, and four coccygeal bones fuse to form...
01:28Articulations of the Vertebral Column