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Clinical Profile of HLA-B27-Associated Uveitis in an Egyptian Cohort
Eiman Abd El Latif1, Ahmed Shawkat Abdelhalim2
1Department of Ophthalmology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Purpose:
To describe the clinical profile of patients with HLA-B27-associated uveitis at 2 Egyptian tertiary eye centers.
Methods:
A retrospective study reviewing the medical records of all patients with HLA-B27-associated uveitis served at 2 uveitis referral clinics in Egypt between January 2010 and June 2018.
Results:
The study included a total of 554 patients. Anterior uveitis was the most common type. Ankylosing spondylitis was an important systemic comorbidity in the present study, affecting 27.4% of our patients. Cataract was the most frequent ocular complication. By the conclusion of the study, 6.1% of the affected eyes had a BSCVA poorer than 20/200.
Conclusion:
The clinical profile of HLA-B27-associated uveitis in our cohort of Egyptian patients is similar to that reported from other regions of the world. In our study, a relatively high rate of cataract was observed.
