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Published on: December 17, 2021
Etiology of Pediatric Uveitis in a Tertiary Pediatric Eye Hospital in Egypt
Eiman Abd El Latif1, Rasha Mousa2, Mohammed Tawfeeq Mahdi3
1Department of Ophthalmology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Insights
This study identified the causes of childhood-onset uveitis in Egyptian children. Intermediate uveitis was most common, with juvenile idiopathic arthritis, toxoplasmosis, and Vogt-Koyanagi-Harada syndrome being leading causes.
Area of Science:
- Ophthalmology
- Pediatric Medicine
- Immunology
Background:
- Childhood-onset uveitis is a significant cause of pediatric vision impairment.
- Understanding the etiological spectrum is crucial for effective management.
Purpose of the Study:
- To determine the prevalence of different anatomical types of childhood-onset uveitis.
- To identify the primary causes of uveitis in pediatric patients in Egypt.
Main Methods:
- Retrospective analysis of medical records.
- Inclusion of 388 patients diagnosed with uveitis.
- Data collected from a tertiary pediatric ophthalmology hospital in Egypt between 2017 and 2020.
Main Results:
- Intermediate uveitis was the most frequent type (30.4%), with pars planitis being common.
- Panuveitis (25.5%), posterior uveitis (23.5%), and anterior uveitis (20.6%) followed.
- Key causes included juvenile idiopathic arthritis (anterior), toxoplasmosis (posterior), and Vogt-Koyanagi-Harada syndrome (panuveitis).
- Common complications were cataract (40.5%), glaucoma (33.8%), and cystoid macular edema (31.6%).
Conclusions:
- This report details the relative prevalence of uveitis types and their causes in Egyptian children.
- Findings contribute to the understanding of pediatric uveitis epidemiology in the region.
Purpose:
To report the causes of childhood-onset uveitis in a tertiary pediatric ophthalmology hospital in Egypt.
Methods:
Retrospective study of the medical records of all uveitis patients following up at a tertiary pediatric ophthalmology hospital in Egypt from January 2017 to December 2020.
Results:
The present study included 388 patients. The most common anatomical category was intermediate uveitis (30.4%), and around half of these children had pars planitis. This was followed by panuveitis (25.5%), posterior uveitis (23.5%), and anterior uveitis (20.6%), in decreasing frequency. Juvenile idiopathic arthritis, toxoplasmosis, and Vogt-Koyanagi-Harada syndrome were the most common causes of anterior uveitis, posterior uveitis, and panuveitis respectively. Cataract (40.5%), glaucoma (33.8%), and cystoid macular edema (31.6%) were the most frequent ocular complications.
Conclusion:
The present report provides the relative prevalence of the different anatomical types of uveitis, as well as their main causes in a cohort of Egyptian patients with childhood-onset uveitis.
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