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Acute Imidacloprid Poisoning in Thailand
Charuwan Sriapha1, Satariya Trakulsrichai1,2, Achara Tongpoo1
1Ramathibodi Poison Center, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
Acute imidacloprid poisoning typically results in mild toxicity, though severe outcomes can occur. Close monitoring is advised for patients ingesting large amounts or exhibiting specific warning signs like cardiovascular or central nervous system effects.
Area of Science:
- Toxicology
- Environmental Health
- Clinical Medicine
Background:
- Imidacloprid is a widely used neonicotinoid insecticide.
- Evidence suggests potential toxicity despite its perceived safety.
- Characterizing acute imidacloprid poisoning is crucial.
Purpose of the Study:
- To characterize clinical manifestations of acute imidacloprid poisoning.
- To identify outcomes associated with imidacloprid exposure.
- To inform clinical management and risk assessment.
Main Methods:
- Retrospective study design.
- Data collected from Ramathibodi Poison Center (2010-2018).
- Inclusion of patients with imidacloprid-only exposure.
Main Results:
- 163 patients analyzed, mostly via ingestion (93.3%).
- Common symptoms: gastrointestinal (63.8%) and neurological (14.2%).
- Low mortality rate (3.1%), but severe outcomes linked to ingestion amount, cardiovascular/CNS effects, dyspnea, and diaphoresis.
Conclusions:
- Most imidacloprid poisoning cases present with mild toxicity.
- A low mortality rate exists, with some mild cases resulting in death.
- Vigilant monitoring is recommended for high-risk ingestions and specific clinical signs.
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