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Lamellar Keratoplasty for Advanced Keratoconus
Moushmi Patil1, Jodhbir S Mehta1,2,3
1Singapore National Eye Centre, Singapore.
Asia-Pacific Journal of Ophthalmology (Philadelphia, Pa.)
|November 19, 2020
Summary
Early diagnosis of ectatic corneal diseases prevents progression. Anterior lamellar keratoplasty (ALK) offers better outcomes than penetrating keratoplasty for advanced cases.
Area of Science:
- Ophthalmology
- Corneal Diseases
- Surgical Techniques
Background:
- Ectatic corneal diseases cause progressive corneal steepening and thinning.
- Includes conditions like keratoconus, keratoglobus, pellucid marginal degeneration, and post-keratorefractive/graft ectasia.
- Early diagnosis is crucial to prevent disease progression and avoid corneal transplantation.
Purpose of the Study:
- To review surgical techniques in anterior lamellar keratoplasty (ALK).
- To evaluate the clinical outcomes of ALK in advanced keratoconus.
- To compare ALK with penetrating keratoplasty for advanced corneal ectasia.
Main Methods:
- Review of surgical techniques for ALK.
- Analysis of clinical outcomes data for ALK in advanced keratoconus.
- Comparison of ALK with penetrating keratoplasty outcomes.
Main Results:
- Anterior lamellar keratoplasty (ALK) is preferred over penetrating keratoplasty for advanced corneal ectasia.
- ALK offers reduced graft rejection, fewer long-term complications, and better graft survival.
- Visual outcomes of ALK are comparable to penetrating keratoplasty, especially in keratoconus.
Conclusions:
- ALK is a preferred surgical option for advanced keratoconus.
- ALK provides significant benefits regarding graft survival and complication rates.
- Timely surgical intervention with ALK can preserve vision and reduce the need for more invasive procedures.

