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Periurethral Lidocaine Does Not Decrease Pain After Urodynamic Testing in Women: A Double-Blinded Randomized Control

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Topical 2% lidocaine gel did not reduce pain after urodynamic testing in women compared to a water-based lubricant. Most women experienced minimal discomfort during the procedure.

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Area of Science:

  • Urology
  • Anesthesiology

Background:

  • Urodynamic testing is common for evaluating lower urinary tract symptoms in women.
  • The procedure can cause discomfort, prompting research into pain management strategies.

Purpose of the Study:

  • To assess the efficacy of periurethral 2% lidocaine gel in reducing pain after complex urodynamic testing in women.

Main Methods:

  • A prospective, double-blinded, placebo-controlled randomized trial was conducted.
  • Participants received either 2% lidocaine gel or a water-based lubricant applied periurethrally before testing.
  • Pain was measured using a Visual Analog Scale (VAS) at multiple time points.

Main Results:

  • No significant difference in the change in VAS scores was observed between the lidocaine and lubricant groups at 4-6 hours post-procedure.
  • Secondary outcome measures, including pain scores at other time points and adverse events, also showed no significant differences.

Conclusions:

  • Periurethral application of 2% lidocaine gel does not effectively decrease pain following urodynamic testing in women.
  • Complex urodynamic testing is generally not associated with significant pain for most women.