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Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
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Related Experiment Video

Updated: Nov 29, 2025

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
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A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing

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Four Quadrant-Embedded Purse-String Closure for Defects of Benign Skin Tumors Post Circular Excision.

Alper Ural1, Fatma Bilgen1, Mehmet Bekerecioglu1

  • 1Department of Plastic, Reconstructive and Aesthetic Surgery, Kahramanmaras Sutcu Imam University School of Medicine, Kahramanmaras, Turkey.

The Eurasian Journal of Medicine
|November 19, 2020
PubMed
Summary
This summary is machine-generated.

The four quadrant embedded purse-string suture technique effectively closes round skin defects after tumor removal, resulting in minimal scarring and high patient satisfaction. This method offers a superior cosmetic outcome compared to traditional linear closures.

Keywords:
Benign skin tumorsdermatologic surgeryskin lesions

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A Mouse Fetal Skin Model of Scarless Wound Repair
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Area of Science:

  • Dermatology
  • Plastic Surgery
  • Wound Healing

Background:

  • Linear suturing of skin wounds from benign tumor excision often leads to undesirable, elongated scars.
  • Alternative closure techniques are needed to improve cosmetic outcomes.

Purpose of the Study:

  • To evaluate the efficacy of the four quadrant embedded intradermal purse-string suture technique for closing round skin defects.
  • To achieve satisfactory cosmetic results with limited scarring.

Main Methods:

  • Analyzed 143 patients with 208 four quadrant embedded purse-string sutures for surgical defect closure.
  • Tumor locations (cervicofacial, thoracic, back, extremities) and histopathology were recorded.
  • Patient and Observer Scar Assessment Scale (POSAS) was used to evaluate scar outcomes.

Main Results:

  • The four quadrant embedded purse-string suture technique resulted in good wound healing with minimal adverse events.
  • Postoperative infection rate was low (3 patients).
  • Satisfactory cosmetic results were achieved, with POSAS scores of 17.74 (patient) and 15.3 (observer).

Conclusions:

  • The four quadrant embedded purse-string technique is a simple and effective method for closing skin defects after circular lesion resection.
  • This technique offers minimal scarring and high patient satisfaction.