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Systematic imaging in medicine: a comprehensive review.
Kai Zhang1,2, Yujie Sun3, Shuang Wu1
1Department of Nuclear Medicine and PET center, The Second Hospital of Zhejiang University School of Medicine, No. 88 Jiefang Road, Hangzhou, 310009, Zhejiang, China.
Systematic imaging offers a comprehensive approach to disease detection by analyzing molecular, functional, and structural changes. Advancements in imaging technology and artificial intelligence are key to its future success.
Area of Science:
- Biomedical imaging
- Medical diagnostics
- Translational medicine
Background:
- Classical diagnostic imaging focuses on specific aspects of disease.
- Systematic imaging aims for a holistic, multi-scale analysis of biological processes.
- Current diagnostic methods may miss interconnected molecular, functional, and structural alterations.
Purpose of the Study:
- To define and advocate for systematic imaging as a comprehensive diagnostic approach.
- To highlight recent advancements enabling systematic imaging.
- To discuss the future potential of systematic imaging in healthcare.
Main Methods:
- Review of recent developments in imaging modalities.
- Exploration of novel nanoparticles-based imaging agents.
- Discussion on the integration of artificial intelligence in imaging.
Main Results:
- Systematic imaging identifies abnormalities across molecular, functional, and structural levels.
- Improvements in imaging instruments and agents are crucial.
- Artificial intelligence is essential for advancing systematic imaging.
Conclusions:
- Systematic imaging provides a comprehensive characterization of diseases.
- It enables effective image-guided therapy and precise treatment evaluation.
- This approach will accelerate pharmaceutical development and improve patient outcomes.
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