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Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
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Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
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Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
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Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

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The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
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Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters
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[COVID-19 and asthma].

R Louis1, D Calmes1, A N Frix1

  • 1Service d'Allergologie-Pneumologie, CHU Liège, Belgique.

Revue Medicale De Liege
|November 19, 2020
PubMed
Summary
This summary is machine-generated.

Asthma patients generally face no increased risk from SARS-CoV-2 infection or severe outcomes. However, severe asthma cases with comorbidities may be at higher risk, while inhaled corticosteroids might offer protection.

Keywords:
AsthmaCorticoids – BiologicalsDeath19COVID

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Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Virology

Background:

  • The SARS-CoV-2 pandemic raised concerns about increased hospitalizations for asthma exacerbations.
  • Respiratory viruses are known triggers for asthma flare-ups.

Purpose of the Study:

  • To investigate the association between asthma and SARS-CoV-2 infection severity.
  • To evaluate the impact of asthma medications on COVID-19 outcomes.

Main Methods:

  • Analysis of patient data regarding asthma status and COVID-19 infection.
  • Assessment of the role of inhaled corticosteroids (ICS) and biological therapies.

Main Results:

  • Asthma is not identified as a significant risk factor for SARS-CoV-2 infection or mortality.
  • Inhaled corticosteroids (ICS) may decrease ACE2 receptor expression, potentially reducing infection risk.
  • Severe asthmatics with comorbidities or on oral steroids/high-dose ICS showed increased mortality risk.
  • Biological therapies targeting IgE or interleukin-5 did not appear to increase severe infection risk.

Conclusions:

  • Most asthma patients do not face heightened risks from SARS-CoV-2.
  • Severe asthma, particularly with comorbidities, warrants careful monitoring during the pandemic.
  • Current asthma management strategies, including ICS, seem safe concerning COVID-19.
  • Targeted biologicals for asthma do not elevate the risk of severe SARS-CoV-2 infection.