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Japanese guidelines for allergic conjunctival diseases 2020
Dai Miyazaki1, Etsuko Takamura2, Eiichi Uchio3
1Division of Ophthalmology and Visual Science, Faculty of Medicine, Tottori University, Tottori, Japan.
Allergic conjunctival diseases, including allergic conjunctivitis and vernal keratoconjunctivitis, involve Type I allergies. Diagnosis requires identifying allergic reactions, with antiallergic eye drops as the primary treatment.
Area of Science:
- Ophthalmology
- Allergy and Immunology
- Clinical Management Guidelines
Background:
- Allergic conjunctival disease is a Type I allergic inflammatory condition of the conjunctiva.
- It presents with subjective symptoms like itching and objective signs such as conjunctival hyperemia.
- Specific forms include allergic conjunctivitis, atopic keratoconjunctivitis, vernal keratoconjunctivitis, and giant papillary conjunctivitis.
Purpose of the Study:
- To summarize the definition, classification, pathogenesis, diagnostic methods, clinical findings, and therapies for allergic conjunctival disease.
- To provide an overview based on the 2019 Guidelines for Clinical Management of Allergic Conjunctival Disease.
Main Methods:
- Review and synthesis of information from the 2019 Guidelines for Clinical Management of Allergic Conjunctival Disease.
- Focus on diagnostic criteria, clinical manifestations, and therapeutic strategies.
Main Results:
- Allergic conjunctival disease is characterized by Type I allergy, presenting with ocular itching, hyperemia, and conjunctival swelling.
- Vernal keratoconjunctivitis involves giant papillae and corneal lesions, causing foreign body sensation, pain, and photophobia.
- Diagnosis confirms Type I allergic reactions in the conjunctiva.
Conclusions:
- First-line treatment involves antiallergic eye drops, with steroid eye drops used for more severe cases.
- Immunosuppressive eye drops are adjunctively used for vernal keratoconjunctivitis treatment.
- Adherence to clinical management guidelines ensures appropriate diagnosis and therapy for allergic conjunctival diseases.
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