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Myocardial involvement in coronavirus disease 19

Ahmed Saleh1, Akira Matsumori2, Sherif Abdelrazek3

  • 1Klinikum Braunschweig, Academic Hospital of Hannover Medical School, Braunschweig, Germany. salehcardio@hotmail.com.

Herz
|November 20, 2020
PubMed

Insights

Coronavirus disease 2019 (COVID-19) frequently causes myocardial injury and impaired heart function. However, cardiac monitoring is crucial as no correlation was found between cardiac values and mortality in COVID-19 patients.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Virology

Background:

  • The COVID-19 pandemic, caused by SARS-CoV-2, has been linked to cardiovascular issues, similar to previous SARS infections.
  • A significant number of COVID-19 patients present with pre-existing cardiovascular disease.
  • Limited data exist on the cardiovascular burden following viral epidemics.

Purpose of the Study:

  • To evaluate the extent of cardiac involvement in patients diagnosed with COVID-19.
  • To investigate the impact of SARS-CoV-2 on cardiac tissues.

Main Methods:

  • Prospective cohort study of 40 adult inpatients diagnosed with COVID-19.
  • Inclusion criteria followed WHO interim guidance.
  • Assessment included laboratory parameters, electrocardiography, and echocardiography to determine cardiac impact.

Main Results:

  • Confirmed a relationship between acute cardiac injury and COVID-19 infection.
  • Myocardial injury and impaired function were common findings in COVID-19 patients.

Conclusions:

  • COVID-19 frequently leads to myocardial injury and functional impairment.
  • No correlation was found between cardiac laboratory values or echocardiographic findings and patient mortality.
  • Routine cardiovascular monitoring is essential for assessing the cardiac burden in COVID-19 patients.
Abstract

Keywords:
COVID-19Cardiac troponin TCardiovascular diseaseNT-proBNPSARS-CoV‑2

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