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3D/4D Reconstruction and Quantitative Total Body Imaging
Jinyi Qi1, Samuel Matej2, Guobao Wang3
1Department of Biomedical Engineering, University of California, One Shields Avenue, Davis, CA 95616, USA.
PET Clinics
|November 21, 2020
Summary
Total-body positron emission tomography (PET) image reconstruction enables simultaneous full-body scans, advancing dynamic PET imaging. This work explores 3D and 4D reconstruction methods, discussing challenges and opportunities for total-body PET.
Area of Science:
- Medical Imaging
- Nuclear Medicine
- Image Reconstruction
Background:
- Standard whole-body PET scanners have limitations in simultaneous coverage.
- Total-body PET scanners offer simultaneous coverage of the entire human body.
- This facilitates total-body dynamic PET scans, enhancing imaging capabilities.
Purpose of the Study:
- To provide an overview of PET image reconstruction basics.
- To focus on three- and four-dimensional (4D) PET reconstruction for total-body imaging.
- To discuss methods, challenges, and opportunities in total-body PET image reconstruction.
Main Methods:
- Describes image formation from raw measurements in total-body PET.
- Covers fundamental principles of PET image reconstruction.
- Focuses on advanced 3D and 4D reconstruction techniques.
Main Results:
- Total-body PET reconstruction shares similarities with standard scanners but enables unique dynamic imaging protocols.
- Four-dimensional dynamic PET reconstruction and parametric imaging are key areas of interest.
- Methods for image formation and reconstruction are detailed, highlighting specific considerations for total-body scanners.
Conclusions:
- Total-body PET imaging presents new possibilities for dynamic scanning and parametric imaging.
- Further research into 3D and 4D reconstruction is crucial for optimizing total-body PET.
- Addressing the challenges and leveraging opportunities will advance the field of total-body PET imaging.
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